![Darzalex (Daratumumab): First Anti-CD38 Monoclonal Antibody Approved for Patients with Relapsed Multiple Myeloma Darzalex (Daratumumab): First Anti-CD38 Monoclonal Antibody Approved for Patients with Relapsed Multiple Myeloma](https://www.theoncologypharmacist.com/images/jhop/2016/JHOPPayersGuide/JHOP_March2016_SpecialEdition_Vol6_Pg38_Tbl2_efficacy_outcomes_gen501.png)
Darzalex (Daratumumab): First Anti-CD38 Monoclonal Antibody Approved for Patients with Relapsed Multiple Myeloma
![Frontiers | Perspectives for the Development of CD38-Specific Heavy Chain Antibodies as Therapeutics for Multiple Myeloma Frontiers | Perspectives for the Development of CD38-Specific Heavy Chain Antibodies as Therapeutics for Multiple Myeloma](https://www.frontiersin.org/files/Articles/407753/fimmu-09-02559-HTML/image_m/fimmu-09-02559-g001.jpg)
Frontiers | Perspectives for the Development of CD38-Specific Heavy Chain Antibodies as Therapeutics for Multiple Myeloma
![Diagnostics | Free Full-Text | Complete Depletion of Daratumumab Interference in Serum Samples from Plasma Cell Myeloma Patients Improves the Detection of Endogenous M-Proteins in a Preliminary Study Diagnostics | Free Full-Text | Complete Depletion of Daratumumab Interference in Serum Samples from Plasma Cell Myeloma Patients Improves the Detection of Endogenous M-Proteins in a Preliminary Study](https://www.mdpi.com/diagnostics/diagnostics-10-00219/article_deploy/html/images/diagnostics-10-00219-g005.png)
Diagnostics | Free Full-Text | Complete Depletion of Daratumumab Interference in Serum Samples from Plasma Cell Myeloma Patients Improves the Detection of Endogenous M-Proteins in a Preliminary Study
![Diagnostics | Free Full-Text | Complete Depletion of Daratumumab Interference in Serum Samples from Plasma Cell Myeloma Patients Improves the Detection of Endogenous M-Proteins in a Preliminary Study Diagnostics | Free Full-Text | Complete Depletion of Daratumumab Interference in Serum Samples from Plasma Cell Myeloma Patients Improves the Detection of Endogenous M-Proteins in a Preliminary Study](https://www.mdpi.com/diagnostics/diagnostics-10-00219/article_deploy/html/images/diagnostics-10-00219-g003.png)
Diagnostics | Free Full-Text | Complete Depletion of Daratumumab Interference in Serum Samples from Plasma Cell Myeloma Patients Improves the Detection of Endogenous M-Proteins in a Preliminary Study
![Figure 1 from Interference of daratumumab in monitoring multiple myeloma patients using serum immunofixation electrophoresis can be abrogated using the daratumumab IFE reflex assay (DIRA) | Semantic Scholar Figure 1 from Interference of daratumumab in monitoring multiple myeloma patients using serum immunofixation electrophoresis can be abrogated using the daratumumab IFE reflex assay (DIRA) | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/cc36ecafc3b7153061997d35df327c462b90b3fe/2-Figure1-1.png)
Figure 1 from Interference of daratumumab in monitoring multiple myeloma patients using serum immunofixation electrophoresis can be abrogated using the daratumumab IFE reflex assay (DIRA) | Semantic Scholar
![Monitoring the M-protein of multiple myeloma patients treated with a combination of monoclonal antibodies: the laboratory solution to eliminate interference Monitoring the M-protein of multiple myeloma patients treated with a combination of monoclonal antibodies: the laboratory solution to eliminate interference](https://www.degruyter.com/document/doi/10.1515/cclm-2021-0399/asset/graphic/j_cclm-2021-0399_fig_002.jpg)
Monitoring the M-protein of multiple myeloma patients treated with a combination of monoclonal antibodies: the laboratory solution to eliminate interference
![Monitoring multiple myeloma patients treated with daratumumab: teasing out monoclonal antibody interference Monitoring multiple myeloma patients treated with daratumumab: teasing out monoclonal antibody interference](https://www.degruyter.com/document/doi/10.1515/cclm-2015-1031/asset/graphic/j_cclm-2015-1031_fig_001.jpg)
Monitoring multiple myeloma patients treated with daratumumab: teasing out monoclonal antibody interference
![Investigation into the interference of the monoclonal antibody daratumumab on the free light chain assay. | Semantic Scholar Investigation into the interference of the monoclonal antibody daratumumab on the free light chain assay. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/0bf788ee5c041d2e4bc185959acf4294830d5ad9/2-Table1-1.png)
Investigation into the interference of the monoclonal antibody daratumumab on the free light chain assay. | Semantic Scholar
![DARZALEX® (daratumumab) Approved by U.S. FDA in Combination with Two Standard of Care Regimens for the Treatment of Patients with Multiple Myeloma Who Have Received At Least One Prior Therapy DARZALEX® (daratumumab) Approved by U.S. FDA in Combination with Two Standard of Care Regimens for the Treatment of Patients with Multiple Myeloma Who Have Received At Least One Prior Therapy](https://www.multivu.com/players/English/7979851-janssen-darzalex-combo-fda-approval/image/darzalex-product-shot-%E2%80%93-400mg-vial-3-HR.jpg)
DARZALEX® (daratumumab) Approved by U.S. FDA in Combination with Two Standard of Care Regimens for the Treatment of Patients with Multiple Myeloma Who Have Received At Least One Prior Therapy
![Investigation into the interference of the monoclonal antibody daratumumab on the free light chain assay - ScienceDirect Investigation into the interference of the monoclonal antibody daratumumab on the free light chain assay - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0009912016301758-gr1.jpg)
Investigation into the interference of the monoclonal antibody daratumumab on the free light chain assay - ScienceDirect
![Implications for the monitoring of patients with multiple myeloma undergoing treatment with the anti-CD38 monoclonal daratumumab - Sally Thirkettle, Joanne Russell, Sarah Wilson, Tasneem Ganijee, Samar Kulkarni, Jim Cavet, Phillip J Monaghan, Implications for the monitoring of patients with multiple myeloma undergoing treatment with the anti-CD38 monoclonal daratumumab - Sally Thirkettle, Joanne Russell, Sarah Wilson, Tasneem Ganijee, Samar Kulkarni, Jim Cavet, Phillip J Monaghan,](https://journals.sagepub.com/cms/10.1177/0004563219894354/asset/images/large/10.1177_0004563219894354-fig1.jpeg)
Implications for the monitoring of patients with multiple myeloma undergoing treatment with the anti-CD38 monoclonal daratumumab - Sally Thirkettle, Joanne Russell, Sarah Wilson, Tasneem Ganijee, Samar Kulkarni, Jim Cavet, Phillip J Monaghan,
![Current use of monoclonal antibodies in the treatment of multiple myeloma - Varga - 2018 - British Journal of Haematology - Wiley Online Library Current use of monoclonal antibodies in the treatment of multiple myeloma - Varga - 2018 - British Journal of Haematology - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/f38f84db-4651-4ced-ab3d-cba1f5f83c40/bjh15121-fig-0002-m.jpg)
Current use of monoclonal antibodies in the treatment of multiple myeloma - Varga - 2018 - British Journal of Haematology - Wiley Online Library
![Addition of daratumumab to multiple myeloma backbone regimens significantly improves clinical outcomes: a systematic review and meta-analysis of randomised controlled trials | Scientific Reports Addition of daratumumab to multiple myeloma backbone regimens significantly improves clinical outcomes: a systematic review and meta-analysis of randomised controlled trials | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-021-01440-x/MediaObjects/41598_2021_1440_Fig1_HTML.png)
Addition of daratumumab to multiple myeloma backbone regimens significantly improves clinical outcomes: a systematic review and meta-analysis of randomised controlled trials | Scientific Reports
![U.S. Food and Drug Administration Approves DARZALEX FASPRO™ (daratumumab and hyaluronidase-fihj), a New Subcutaneous Formulation of Daratumumab in the Treatment of Patients with Multiple Myeloma U.S. Food and Drug Administration Approves DARZALEX FASPRO™ (daratumumab and hyaluronidase-fihj), a New Subcutaneous Formulation of Daratumumab in the Treatment of Patients with Multiple Myeloma](https://mma.prnewswire.com/media/1160433/Darzalex_Faspro.jpg?p=facebook)
U.S. Food and Drug Administration Approves DARZALEX FASPRO™ (daratumumab and hyaluronidase-fihj), a New Subcutaneous Formulation of Daratumumab in the Treatment of Patients with Multiple Myeloma
![Efficacy and safety of daratumumab combined with all-trans retinoic acid in relapsed/refractory multiple myeloma - ScienceDirect Efficacy and safety of daratumumab combined with all-trans retinoic acid in relapsed/refractory multiple myeloma - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2473952921007138-grabsf1.jpg)